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Young Bok Abraham Kang
East Portland, Oregon, United States
bio
Dr. Kang holds a bachelor’s degree and master’s degree in biological and chemical engineering from Korea University and Seoul National University, respectively. He holds a Ph.D. degree in mechanical engineering and mechanics from Drexel University. During his master’s degree program (2002-2004), he studied the biosynthesis of anti-biotic precursors through combined enzymatic pathways. After graduation, he worked in Celltrion Inc. as a Quality Assurance Manager for over seven years, which is a biopharmaceutical company to produce monoclonal antibody drugs for cancer therapy (2004-2011). In the year 2011-2015 for his Ph.D. program, he studied the development of a novel human liver model that closely mimics the architecture and function of the liver sinusoid by using microfluidic devices. His human liver chip was used in demonstrating Hepatitis B virus (HBV) replication. He was further involved in several projects; 1) microdroplet generation, 2) flow-induced voltage generation over monolayer graphene in the presence of herring-bone grooves, and 3) microchannel-guided peripheral neural growth. As a postdoctoral researcher at the Center for Engineering in Medicine (CEM) in Harvard Medical School/ Massachusetts General Hospital (2015-2018), he studied the development of novel microfluidic platforms for actively controlled in-vitro liver zonation. He successfully demonstrated the zonation of primary rat/human hepatocytes in carbohydrate, nitrogen, xenobiotics metabolism, oxygen-related metabolism, and drug-induced hepatotoxicity using a microfluidic culture platform with a gradient generator. He was also involved in other projects including long-term perfusion culture of a liver slice, hypoxia model development, and wound tissue chip. At George Fox University (2018-present), he, an associate professor of biomedical engineering (BME), has been providing lectures/labs including Biomaterials, Biotransport, Circuit & Instruments, BioMEMs&Tissue engineering, and Medical device design for undergraduate students. He has been advising undergraduate students on engineering design projects and their research. His research focuses on artificial tissue development (e.g., tumor chip, heart chip, and joint chip) and modeling of tissue physiology for prediction of cell motion by collaborating with Oregon Health & Science University (OHSU). In his other projects, he has been working on microfabrication, 3D bioprinting, biomaterials, an automated system using Arduino and circuit, medical devices, and Biomechanical analysis for lower limb injury prediction. With many years of academic and industrial experience at the intersection of device fabrication with circuit and biomedical engineering, He gained a tremendous amount of knowledge and hands-on experience on subjects ranging from manufacturing with a circuit to drug toxicity test/imaging analysis through cell culture and biological assays. As an outcome, he has published 14 peer-reviewed journal articles in the field of biomedical engineering. He greatly contributed to the improvement of human health and medicine in research as well as the enhancement of education by mentoring, training, and teaching undergraduate/graduate students essential science & engineering knowledge and skills.
bio
Dr. Kang holds a bachelor’s degree and master’s degree in biological and chemical engineering from Korea University and Seoul National University, respectively. He holds a Ph.D. degree in mechanical engineering and mechanics from Drexel University. During his master’s degree program (2002-2004), he studied the biosynthesis of anti-biotic precursors through combined enzymatic pathways. After graduation, he worked in Celltrion Inc. as a Quality Assurance Manager for over seven years, which is a biopharmaceutical company to produce monoclonal antibody drugs for cancer therapy (2004-2011). In the year 2011-2015 for his Ph.D. program, he studied the development of a novel human liver model that closely mimics the architecture and function of the liver sinusoid by using microfluidic devices. His human liver chip was used in demonstrating Hepatitis B virus (HBV) replication. He was further involved in several projects; 1) microdroplet generation, 2) flow-induced voltage generation over monolayer graphene in the presence of herring-bone grooves, and 3) microchannel-guided peripheral neural growth. As a postdoctoral researcher at the Center for Engineering in Medicine (CEM) in Harvard Medical School/ Massachusetts General Hospital (2015-2018), he studied the development of novel microfluidic platforms for actively controlled in-vitro liver zonation. He successfully demonstrated the zonation of primary rat/human hepatocytes in carbohydrate, nitrogen, xenobiotics metabolism, oxygen-related metabolism, and drug-induced hepatotoxicity using a microfluidic culture platform with a gradient generator. He was also involved in other projects including long-term perfusion culture of a liver slice, hypoxia model development, and wound tissue chip. At George Fox University (2018-present), he, an associate professor of biomedical engineering (BME), has been providing lectures/labs including Biomaterials, Biotransport, Circuit & Instruments, BioMEMs&Tissue engineering, and Medical device design for undergraduate students. He has been advising undergraduate students on engineering design projects and their research. His research focuses on artificial tissue development (e.g., tumor chip, heart chip, and joint chip) and modeling of tissue physiology for prediction of cell motion by collaborating with Oregon Health & Science University (OHSU). In his other projects, he has been working on microfabrication, 3D bioprinting, biomaterials, an automated system using Arduino and circuit, medical devices, and Biomechanical analysis for lower limb injury prediction. With many years of academic and industrial experience at the intersection of device fabrication with circuit and biomedical engineering, He gained a tremendous amount of knowledge and hands-on experience on subjects ranging from manufacturing with a circuit to drug toxicity test/imaging analysis through cell culture and biological assays. As an outcome, he has published 14 peer-reviewed journal articles in the field of biomedical engineering. He greatly contributed to the improvement of human health and medicine in research as well as the enhancement of education by mentoring, training, and teaching undergraduate/graduate students essential science & engineering knowledge and skills.